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THE WINNING MOVE FOR THE DIAGNOSIS
OF AUTOIMMUNE DISEASES

 

Eurospital Autoimmunity Product Line (EAL) offers a range of first and second level tests as a support for the diagnosis of autoimmune diseases.

Autoimmune diseases are chronic pathologies characterized by inflammatory and immune reactions against self antigens, which can be both systemic and organ-specific.
The search for circulating autoantibodies is essential for the diagnosis of these diseases, including rheumatoid arthritis, multiple sclerosis, systemic lupus erythematosus and scleroderma.

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LUPUS-LIKE DISORDERS

Detection of autoantibodies anti cardiolipin, B2GPI and phospholipid antigens

ELISA tests for the determination of IgG and IgM antibodies against cardiolipin, beta-2 glicoprotein I (B2GPI) and phospholipid antigens, in human serum and plasma samples, for the diagnosis of Antiphospholipid Syndrome and Lupus-like disorders.

  • Eu-ACA G/M (Cod. 7600)
  • Eu-ACA A (Cod. 7601)
  • Eu-BGPI G/M (Cod. 7603)
  • Eu-PS S G/M (Cod. 7606)

REUMATHIC DISEASE

Detection of autoantibodies anti antigens and CCP

ELISA tests for the determination of IgG antibodies against nuclear antigens (ANA ed EMA) and cyclic citrullinated peptide (CCP), in human serum and plasma samples, for the diagnosis of systemic reumathic disease.

  • Eu-ANA S (Cod. 7614)
  • Eu-8 ENA S (Cod. 7615)
  • Eu-8 ENA Pr (Cod. 7618)
  • Eu-CCP (Cod. 7631)

VASCULITIS

Detection of autoantibodies anti PR3 and MPO

ELISA tests for the determination of IgG antibodies against proteinase 3 (PR3) e myeloperoxidase (MPO), in human serum and plasma samples, for the diagnosis of Vasculitis.

  • Eu-PR3+ (Cod. 7646)
  • Eu-MPO (Cod. 7647)

DIABETES

Detection of autoantibodies anti Insulin

ELISA test for the determination of IgG antibodies against Bovine, Porcine and human recombinant insulin in serum samples, for the diagnosis of Diabetes.

  • Eu – Insulin (Cod. 7652)

COELIAC DISEASE

Detection of autoantibodies involved in coeliac disease

IFA tests (Immunofluorescenza indiretta) for the determination of IgG /IgA anti-endomysial antibodies on sections of the lower third of monkey esophagus from human serum samples or intestinal biopsies.

  • Antiendomysium IgA (4 wells) (Cod. 8734)
  • Antiendomysium IgA (8 wells) (Cod. 8738)
  • Antiendomysium IgG (8 wells) (Cod. 8721)
  • Antiendomysium Biopsy (Cod. 8726)
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OTHER TESTS

ELISA tests for the detection of autoantibodies involved in autoimmune disease

ELISA tests for the determination of IgG/IgM antibodies against prothrombin and mitochondrial antigen (M2 subtype) in human serum or plasma samples.

  • Eu-Prothrombin G/M (Cod. 7610)
  • Eu-AMA M2 (Cod. 7651)

Immunoblot for the diagnosis of autoimmune hepatitis

Immunoblot for the determination of autoantibodies against AMA M2, Sp100, gp210, SLA/LP, LKM-1, LC-1, F-actin, Actinin and Tropomyosin in human serum and plasma samples.

  • Eu-Liver Blot (Cod. 7673)

IFA tests for the detection of autoantibodies involved in autoimmune disease

IFA tests (Immunofluorescenza indiretta) for the determination of IgG autoantibodies anti nuclear antigens in human serum samples.

  • ANA – Hep2 (Cod. 6948)
  • ANA, AMA, ASMA, APCA, LKM (Cod. 6949)
  • nDNA IFA (Cod. 6950)